Hauj lwm lawm

Kev tsis

Tetracaine (tetracaine) Raw Khoom Hmoov Core Taw Qhia

Kws muag tshuaj -} qib raw cov ntaub ntawv|Tetracaine (ntev - ua yeeb yam ester ester hauv zos anesthetic)

Tshuaj lom neeg npe: 2- (dimethylamino) Ethyl-4- (Butylamino) Benzoate

Tus lej: 94-24-6

Einecs tooj: 202-318-6

Molecular Cov Lus: C₁₅h₂₄n₂o₂

Molecular hnyav: 264.36

Melting Taw tes: 41-42 Qib

Zog: Dawb Crystalline Hmoov

Solubility: me ntsis soluble hauv dej, yooj yim soluble hauv ethanol thiab chloroform

PKA tus nqi: 8.2-8.5

Muab faib coefficient: Teev P =3.5 (octanol / Dej)

Cov khoom tseem ceeb

Tetracaine yog antev - Ua yeeb yam eser Intertyeticdav siv rauKev tshuaj loog nti cov tshuaj loog, infiltration anteshesia, thiab tus txha caj qaumVim nwsmuaj hwj huam ntxig tshuaj loog thiab ntev -} kav cov nyhuv.

✅ Pharmacological cov zog:

Muaj zog anesthetic nyhuv: 10 zaug lub anesthetic lub zog ntawm procaine

Moderate Hnub Poob Sijhawm: Aesthaesia nto siv sijhawm 3-5 feeb los siv cov nyhuv

Ntev -} kav cov nyhuv: Cov nyhuv tshuaj loog tuaj yeem ntev li 2-3 teev

✅ Pharmaconinetics:

Kev Taw Qhia Kev Taw Qhia Kev Ncaws Pob: Hydrolyzed los ntawm Esterase hauv Ntshav

Metabolites: hydrolyzed rau hauv 4-butylaminobenzoic acid thiab dimethylaminoethanol

Ua rau kev pab: Feem ntau yog los ntawm lub raum

✅ Kev Nyab Xeeb Nta:

PIG SIVICAL INCL: Cov npoo ntawm kev ruaj ntseg loj

Tsawg dua kev ua xua: Qhov tshwm sim ntawm kev phiv tsis haum yog qis dua li ntawm lwm cov tshuaj loog hauv zos

Cov ntaub so ntswg zoo sib xws: Tsawg nws voos rau cov ntaub so ntswg hauv zos

Muaj peev xwm kawg cov khoom lag luam thiab cov ntawv thov

1. Cov tshuaj loog anesthoetics (0.5% -2%):

Kev Tsim Daim(Noj 1% daws teeb meem ua piv txwv):

Tetracaine raw khoom: 1.0g

Sodium Chloride: 0.9g (Los kho OSMOTULIC siab)

Dej rau kev txhaj tshuaj: ntxiv rau 100ml

Dosage SCARIANTS:

Qhov muag poob: 0.5% kev xav, rau kev phais mob ophthalmic

Txau: 1% concentration, rau kev ua pa rau kev ua pa

Gel: 2% concentration, siv rau kev ua pauj tshuaj ntsuab

Cov Ntawv Thov Kev Kho Mob:

Ophthalmic phais: corneal lub cev tawm hauv lub cev tshem tawm, ntsuas qhov ntsuas qhov ntsuas

Otorhinolaryngology: Nasal Endoscopy, Laryngoscopy

Dermatology: Tshuaj loog ua ntej - chaw phais tawv nqaij

2. Cov tshuaj loog (0.2% -0.5%):

Tshuaj mis(rau tus txha caj qaum):

Tetracaine Raw Khoom: 0.5g

Cov piam thaj: 5.0g (nce kev daws teeb meem)

Dej rau kev txhaj tshuaj: ntxiv rau 100ml

Kev Npaj Tshwj Xeeb:

Kev daws teeb meem hnyav hnyav: Siv rau txha caj qaum ua rau loog, tswj cov qib ntawm kev ua kom loog

Yog kev daws teeb meem: rau kev pab tshuaj loog tshwj xeeb

Epinephrine -} muaj kev npaj: Lub sijhawm ua kom ntev ntev thiab txo los ntshav

Daim Ntawv Thov Kev Tshuaj Xyuas Ntshav:

Tus txha caj qaum: Qis dua plab thiab txo qis phais

Epidural tshuaj loog: Lub siab xav tau kom muaj kev txo qis

Txoj hlua khi: siv rau kev ua kom loog loog

3. Compound Tshuaj loog:

Kev sib xyaw ua ke:

Tetracaine + Lidocaine: Sib txuas nrawm dua thiab ntev -} kav esteshesia

Tetracaine + procaine: Synergistically txhim kho cov nyhuv tshuaj loog

Tetracaine + epinephrine: LOLLONS ATSESTHESIA LUB SIJ HAWM THIAB PEDUCES TXHEEJ TXHEEM

Ntsej Muag Dosage Daim Ntawv Innovation:

Mucosal Thaj: siv rau lub qhov ncauj mucosal antestesia

Txhawb nqa - tso tawm microspheres: Muab cov nyhuv anestheted

Thermosensitive gel: Lub cev kub ua rau cov gelation kom ua tiav kev ua kom loog

Cov kev siv raws tu qauv

1. Dosage Tswj Cov Cai:

Kev Nyab Xeeb Kev Nyab Xeeb Ntau Yam:

Cov tshuaj loog pleev ib ce: Qhov siab tshaj plaws koob tsis tshaj 50 mg

Infiltration Actionhesia: 0.1% daws, tsis pub ntau tshaj 40 ml ib koob tshuaj

Tus txha caj qaum: 5-10 mg, kho raws li kev phais mob xav tau

Kev Xaiv Qhia Kev Xaiv:

Cov tshuaj loog pleev ib ce: 0.5%-2.0%

Infiltration Actionhesia: 0.05%-0.1%

Txoj hlua khi: 0.1%-0.2%

Tus txha caj qaum: 0.2%-0.5%

2. Cov kev siv tshwj xeeb:

Cov ntaub ntawv tshuaj loog pleev ib ce:

Ocular memeshesia:

0.5% daws, 1-2 dauv txhua zaus

Tuaj yeem siv rov qab tom qab 5 feeb

Tsis pub tshaj 5 zaug hauv 24 teev

Kev ua pa ua pa loog loog:

1% tov tshuaj tsuag, 0.5-1 covml txhua lub sijhawm

Siv 10-15 feeb ua ntej kev ua haujlwm

Tag nrho cov nyiaj tsis tshaj 20ml

Txhaj Tshuaj Txhuam Tshuaj Txhuam Hniav:

Tus txha caj qaum:

0.5% cov kev daws teeb meem tshwj xeeb, kev txhaj tshuaj sai yuav tsum qeeb

Kho cov koob tshuaj raws li qhov chaw phais mob

Saib xyuas ntshav siab thiab ua pa

3. Siv cov neeg tshwj xeeb:

Cov Menyuam Tshuaj:

Nruj me ntsis ua ntau npaum li cas raws li qhov hnyav

Txo cov kev siv zoo

Lub sijhawm luv luv lub sijhawm

Kev noj tshuaj rau cov laus:

Cov Khoom Siv Kom Zoo Tso Tawm

Txuas ntxiv rau kev siv hluav taws xob

Ntxiv dag zog rau cov tseem ceeb tshaj tawm kev soj ntsuam

Daim siab ua haujlwm tsis sib xws:

Siv nrog kev ceev faj, txo cov tshuaj

Txuas ntxiv rau kev siv hluav taws xob

Saib Xyuas Cov Ntshav Ntshav

Vim li cas thiaj xaiv cov khoom siv tetracaine?

Muaj zog anesthetic nyhuv: Cov nyhuv tshuaj loog yog qhov zoo dua li lwm cov tshuaj ester hauv zos

Ntev -} kav cov nyhuv: Kev Tshuaj loog ntev ntev ntev, haum rau ntev -} kev phais mob

Ntau cov ntaub ntawv ntau npaum: Cov ntawv ntau npaum li cas tuaj yeem npaj tau kom tau txais kev pab sib txawv

Kev nyab xeeb zoo: Dav dav dav Performance index thiab tsawg muaj kev fab tshuaj ua xua

Tag

Tetracaine yogIb qho khoom xyaw tseem ceeb hauv kev npaj ntev - ua yeeb yam tshuaj loog hauv zosCov. DhauKev tshawb fawb txuj ci txheej txheem,Nws tuaj yeem ua rau ntau yam kawg - cov khoom, suav nrogCov kev ntsuas tshuaj loog, cov tshuaj loog, thiab kev npaj ua ke. Xaiv peb yuav muab koj lub siab - kev txhawb nqa cov ntaub ntawv, thiab kev pabcuam tom qab {2} Kev pabcuam muag muag.

Xav tau cov txuj ci tshwj xeeb lossis kev qhia txuj ci?

Txais tos tiv toj rau peb cov kws pab txhawb nqa los muab cov kev daws teeb meem!

Xav taudab tsi, thov hu raupeb