Hauj lwm lawm

Kev tsis

Toremifas citrate (Toremifene citrate) Raw Khoom Hmoov Core Taw Qhia

Kws Tshuaj Ua Lag Luam Qib Khoom Qhua Khoom xyaw|Toremifas citrate, ib qho kev xaiv tshuaj estrogen receptor modulator (cov lus qhuab qhia)

Tshuaj lom neeg npe: (Z) - 2 {{}}} {-diphenyl-1-butenyl) phenoxy]-dimethylethylethylastramine citrate

Tus lej: 89778-27-8

Molecular cov mis: C₂₆hennal · C₆h₈o₇

Molecular hnyav: 598.09

Melting taw tes: 108-110 degree

Zog: Dawb lossis tawm -} e} crystalline hmoov

Purity: ntau dua los yog sib npaug rau 98% (HPLC)

Cov teebmeem tseem ceeb

Toremifas citrate yog aXaiv tshuaj estrogen modulator (cov lus qhuab qhia) uasyog siv dav rauKev kho mob cancer mis, kev tiv thaiv ntawm Esrogen -} {{1} {steroid voj voog rov qab (Pct)Vim nwsLub zog muaj zog tshuaj estrogen modulating cov khoom lag luam thiab kev tsim txom zoo.

✅ Lub zog muaj zog tshuaj estrogen receptor kev cai:

Kev sib tw khi rau estrogen receptorsthiab blocks estrogen signaling

Cov nqaij mos -} deadive cuam tshuam, tsim kev laus lossis kev tawm tsam kev cuam tshuam ntawm cov ntaub so ntswg sib txawv

✅ Daim Ntawv Thov Kev Kho Mob Cancer mis:

Estrogen receptor -} 'txoj kev kho cancer zoo, zoo inhibiting cov qog kev loj hlob

Zoo zamthiab muaj kev nyab xeeb rau ntev - tsis siv

✅ Post - Kev Rov Qab Los (PCT):

Txhawb nqa prosogenous sequitosterone zais ciathiab ceev ceev gonadal muaj nuj nqi

Tiv thaiv cov estrogen-}} cov kev mob tshwm sim

✅ Qhov Zoo:

Ntev ib nrab ib nrab - lub neej(5-7 hnub) thiab tsawg dua kev noj haus

Tsawg Hepatotoxicitythiab muaj kev nyab xeeb dua tamoxifen

Ntau daim ntawv thov muaj nuj nqis, tuaj yeem siv tau hauv kev kho mob thiab kis las kis las

Kawg Cov Khoom Qhia Khoom Siv Khoom Taw Qhia

1. Cov ntsiav tshuaj npaj (60 mg / ntsiav tshuaj):

Piv Txwv Piv Txwv(rau 1000 ntsiav tshuaj):

Toremifas citrate raw khoom: 60.0g (xam raws li toremifene)

Microcrystalline Cellulose: 80.0g

Lactose: 50.0g

Hla -} Txuas cov carboxymethyl cellulose sidium: 8.0g

Magnesium Stearate: 2.0g

Npaj txheej txheem:

Cov Khoom Siv Raw Ua Ntej: Micronization (D90 tsawg dua los yog sib npaug rau 10μm)

Cov nqi sib xyaw sib xyaw: maj mam sib tov nrog rau dituent

Ntub av granulle: Granulate nrog cov nyiaj uas tsim nyog ntawm cov dej huv thiab qhuav hauv cov kua hauv 50 degree

Granulation: 20 Mesh Sab Canules, ntxiv Flow AIDS thiab roj nplua nyeem

Ntsiav tshuaj: 8mm round tuag, 8-10kn siab ntsiav tshuaj

Zaj duab xis txheej: Gastro - soluble zaj duab xis txheej kom txhim kho kev ruaj khov thiab palatability

Kev Tswj Xyuas Zoo:

Cov ntsiab lus sib xyaw: RSD tsawg dua lossis sib npaug ntawm 3% (UV {{1} hplc nrhiav kom pom)

Tus lej sib cais: Ntau dua los yog sib npaug rau 85% hauv 30 feeb (duav txheej txheem, 50 rpm)

Lwm yam tshuaj: Ib leeg impurity tsawg dua los yog sib npaug rau 0.5%, tag nrho cov impurities tsawg dua los yog sib npaug rau 1.0%

2. Npaj sau ntawv:

Cov Khoom Siv Raw Khoom Raw: Tripleylethylene derivative, mas photosensitivity

Ib Cheeb Tsam Ntau Lawm: Tus txheeb ze cov av noo tsawg dua los yog sib npaug 40%, zam kev ua haujlwm lub teeb

Ntim yuav tsum tau: Aluminium ntawv ci tshuab ntim, lub teeb - ntawv pov thawj thiab noo noo-

Vim li cas thiaj xaiv cov toremifene?

Ib qho ntawm cov lus muaj kev nyab xeeb tshaj plawsnrog tsawg kawg kev pheej hmoo ntawm hepatotoxicity

Ntev ib nrab ib nrab - lub neej, txo cov nqi zog thiab kev txhim kho yooj yim

Ob lub Luag Haujlwm Pab Nyiaj, tuaj yeem siv rau kev kho mob cancer mis thiab kev rov ua voj voog

Kev Muaj Peev Xwm Zoo:

GMP -} ua tiav ntau lawm, txhua pobHPLC Purity kuaj (loj dua lossis sib npaug rau 98%)

Thib peb - tog kab ke ceeb toom (COA)suav nrog cov khoom

Microbial txwv kuajTxhawm rau kom muaj kev nyab xeeb

Lub Ntiaj Teb Shipping:

Thawj Ntim Ntim Ntim, noo noo - ntawv pov thawj thiab lub teeb- ntawv pov thawj

Ntiav neeg, tsis muaj logo ntawm lub ntim sab nraud

Kub -} tswj kev thauj mus losTxhawm rau kom muaj kev ruaj khov

Tag

Titemifas citrate citrateyuav tsim rau hauv kev siv cov tshuaj lim dej siv cov txheej txheem txheemCov. Nws yog tshwj xeeb rauKev kho mob cancer mis, kev tiv thaiv ntawm estrogen -}} muaj cov kev mob tshwm sim, thiab rov qab tom qab kev sib txuas lus steroidCov. Cov koob tshuaj pom zoo yog60mg / hnub.

Xav taudab tsi, thov hu raupeb