SR9009 Sarms Ua nyob rau hauv Tuam Tshoj High -purity Raw Powder

SR9009 Raw Material Powder Core Taw qhia

Pharmaceutical -qib raw khoom|Ua nyob rau hauv Suav teb SR9009 (Rev-Erb agonist)

Tshuaj npe: (R)-2-([1,1'-biphenyl]-4-yl)-N-((4-chlorophenyl)sulfonyl)-1,2,3,4-tetrahydroquinoline-4-amine

CAS Nr.: 1379686-30-2

EINECS ID: -

Cov mis mos molecular: C₂₂H₂₁ClN₂O₂S

Molecular hnyav: 412.93

Melting pointKub: 198-201 degree

Qhov tshwm sim: Dawb crystalline hmoov

Purity: Ntau dua lossis sib npaug li 99% (HPLC kuaj pom)

Cov teebmeem tseem ceeb

SR9009 yog aRev-Erb nuclear receptor agonistuas yog dav siv nyob rau hauvKev tshawb nrhiav cov kab mob metabolic, kev ua kom muaj zog tiv thaiv, thiab kev tswj hwm circadian atherosclerosisvim nwsCim circadian atherosclerosis tswj mechanism thiab metabolic regulation zog.

✅ Biological moos tswj mechanism:

Rev-Erb activation: Tshwj xeeb activates Rev-Erb nuclear receptor, tswj core circadian atherosclerosis noob.

Kev txhim kho metabolic: Txhim kho kev siv hluav taws xob thiab txhawb cov roj oxidation.

Kev ua siab ntev: Txhim kho VO2 max thiab ua kom muaj zog

✅Qualityqhov zoo ntawm Suav manufacturing:

Purity Guarantee: Raw khoom purity Ntau dua los yog sib npaug rau 99.5%, ua raws li USP cov qauv.

Chirality tswj: (R)-configuration optical purity Ntau dua lossis sib npaug li 99.8%

Zoo heev stability: Purity tseem siab dua 97% tom qab 6 lub hlis ntawm kev ntsuas nrawm.

✅ thoob ntiaj tebmuab kev ruaj ntseg:

Cold chain logistics: -20℃txias saw tsheb thauj mus los thoob plaws tag nrho cov txheej txheem los xyuas kom meej cov khoom ruaj khov.

Ntau- khoom xa tuaj: Cov tsev khaws khoom hauv cheeb tsam tau tsim nyob rau hauv Suav teb, Tebchaws Europe, Amelikas, thiab Asia - cheeb tsam Pacific, ua kom cov khoom xa tuaj hauv 7 hnub.

Kev them nyiaj yug kev lis kev cai clearance: Kev npaj cov ntaub ntawv ua kom muaj kev lis kev cai zoo thoob ntiaj teb.

Cov txheej txheem ntau lawm thiab kev ruaj ntseg zoo

1. Advanced synthesis txheej txheem:

Chiral synthesis: Asymmetric synthesis, (R)-configuration optical purity Ntau dua los yog sib npaug rau 99.8%

Kev ua kom huv huv: Npaj HPLC purification, gradient elution, sau ntawm lub ntsiab ncov.

Tshuab ziab khaub ncaws: Lub tshuab nqus tsev qis- kub kom qhuav, noo noo cov ntsiab lus tsawg dua lossis sib npaug li 0.5%

2. Cov qauv kev tswj xyuas nruj:

Tshuaj purity:

Cov ntsiab lus tseem ceeb: 99.0% ~ 101.0%

Cov khoom muaj feem xyuam: Ib qho impurity Tsawg dua lossis sib npaug li 0.1%, tag nrho impurities Tsawg dua lossis sib npaug li 0.5%

Residual solvent: Ua raws li ICH Q3C cov qauv

Lub cev muaj zog:

Particle loj faib: D50 50-100μm

Qhov ceev: 0.4-0.6 g / cm³

Solubility: Ua tau raws li cov qauv rau cov khoom xyaw tshuaj nquag.

3. Cov ntaub ntawv ruaj ntseg:

Ntev -lub sij hawm ruaj khov: Khaws ntawm -20℃rau 24 lub hlis, txhua qhov ntsuas tau ua tau raws li qhov xav tau.

Kev ntsuas nrawm: Tom qab khaws cia ntawm 25℃rau 6 lub hlis, purity txo qis dua los yog sib npaug li 2.0%.

Kev thauj mus los ruaj khov: Kev vibration thiab poob kev xeem dhau.

Cov yam ntxwv ntawm daim ntawv thov thiab qhov zoo

1. Cov yam ntxwv ua tau zoo:

Txhim kho metabolic: Qhov tseem ceeb nce basal metabolic tus nqi thiab lub zog siv

Txo rog: Txhawb cov roj oxidation thiab txo lub cev rog.

Endurance txhim khu kev qha: Txhim kho kev ua kom muaj zog thiab ua kom cov pa oxygen ntau tshaj.

2. Cov yam ntxwv tseem ceeb thiab qhov zoo:

Lub Hom Phiaj Tshiab: Thawj Rev-Erb lub hom phiaj agonist nrog lub tshuab tshwj xeeb.

Kev tswj hwm metabolic: tswj cov piam thaj thiab lipid metabolism

Biological rhythms: tswj cov kev qhia ntawm cov tseem ceeb roj ntsha moos genes

3. Qhov zoo ntawm kev siv:

Siv tau qhov ncauj: Siab qhov ncauj bioavailability thiab yooj yim rau siv.

Cov ntawv thov tshawb fawb: Cov cuab yeej zoo tshaj plaws rau kev tshawb fawb hauv cov kab mob metabolic thiab cov tshuaj kis las.

Zoo kev nyab xeeb profile: Cov kev tshawb fawb preclinical tau qhia txog kev nyab xeeb zoo.

Vim li cas thiaj xaiv Suav - ua SR9009 ?

Tsim tshiabMechanism: Thawj Rev-Erb lub hom phiaj agonist nrog lub tshuab tshwj xeeb

Chiralkev huv: (R)-configurational optical purity Ntau dua lossis sib npaug li 99.8%

Tshwj xeebkev huv: Tshaj 99% siab purity, nrog kev tswj xyuas nruj.

ruaj khovmuab: Ib qho kev xa khoom tiav ua kom muaj kev xa khoom raws sij hawm thiab txhim khu kev qha.

Cov ntsiab lus

SR9009 raw khoom hmoov, tsim nyob rau hauv Suav teb,sawv cev rau lub siab - qauv zoo ntawm Rev-Erb agonists. Los ntawmadvanced chiral synthesis thev naus laus zis, kev tswj xyuas zoo, thiab cov khoom siv ruaj khov,nws muabsiab -cov cuab yeej tshawb fawb zoo heevrauCov kab mob metabolic thoob ntiaj teb thiab kev tshawb fawb tshuaj ncaws pob. Xaiv "Made in China" txhais tau tias xaivkev tshawb fawb-qib zoo thiab txhim khu kev qha.

Xav taudab tsi, thov hu raupeb

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