S23 Sarms Ua nyob rau hauv Tuam Tshoj High-purity Raw Powder

S23 Raw Material Powder Core Taw qhia

Pharmaceutical -qib raw khoom|Ua nyob rau hauv Suav teb S23 (xaiv androgen receptor modulator)

Tshuaj npe: 4-((R)-2-((R)-2,3-dihydro-1H-inden-1-ylamino)-3,3-dimethylbutyryl)amino-2-(trifluoromethyl)benzylnitrile

CAS Nr.: 431579-34-9

EINECS ID: -

Cov mis mos molecular: C₂₄H₂₅F₃N₄O

Molecular hnyav: 442.48

Melting pointKub: 201-205 degree

Qhov tshwm sim: Dawb crystalline hmoov

Purity: Ntau dua lossis sib npaug li 99% (HPLC kuaj pom)

Cov teebmeem tseem ceeb

S23 yog aKev xaiv ntau androgen receptor modulator (SARM)uas yog dav siv nyob rau hauvkev kho mob ntawm cov leeg nqaij atrophy, kev tiv thaiv thiab kev kho mob osteoporosis, thiab kev tshawb fawb txog kev siv lub cevvim nwsCov qauv arylpropionamide tshwj xeeb thiab ua tiav cov khoom agonist.

✅ Tag nrho agonist mechanism:

Tag nrho cov receptor agonist: androgen receptor full agonist, EC50=1 nM

Cov ntaub so ntswg selectivity: Kev ua haujlwm siab agonistic tau pom hauv cov leeg pob txha thiab pob txha.

Kev cai ntawm noob: tswj kev qhia ntawm androgen teb cov noob

✅Qualityqhov zoo ntawm Suav manufacturing:

Purity Guarantee: Raw khoom purity Ntau dua los yog sib npaug rau 99.5%, ua raws li USP cov qauv.

Chirality tswj: (R, R) configuration optical purity Ntau dua los yog sib npaug rau 99.8%

Zoo heev stability: Purity tseem siab dua 97% tom qab 6 lub hlis ntawm kev ntsuas nrawm.

✅ thoob ntiaj tebmuab kev ruaj ntseg:

Cold chain logistics: -20℃txias saw tsheb thauj mus los thoob plaws tag nrho cov txheej txheem los xyuas kom meej cov khoom ruaj khov.

Ntau- khoom xa tuaj: Cov tsev khaws khoom hauv cheeb tsam tau tsim nyob rau hauv Suav teb, Tebchaws Europe, Amelikas, thiab Asia - cheeb tsam Pacific, ua kom cov khoom xa tuaj hauv 7 hnub.

Kev them nyiaj yug kev lis kev cai clearance: Kev npaj cov ntaub ntawv ua kom muaj kev lis kev cai zoo thoob ntiaj teb.

Cov txheej txheem ntau lawm thiab kev ruaj ntseg zoo

1. Advanced synthesis txheej txheem:

Chiral synthesis: Asymmetric synthesis, (R, R) configuration nrog optical purity Ntau dua los yog sib npaug rau 99.8%.

Kev ua kom huv huv: Npaj HPLC purification, gradient elution, sau ntawm lub ntsiab ncov.

Tshuab ziab khaub ncaws: Lub tshuab nqus tsev qis- kub kom qhuav, noo noo cov ntsiab lus tsawg dua lossis sib npaug li 0.5%

2. Cov qauv kev tswj xyuas nruj:

Tshuaj purity:

Cov ntsiab lus tseem ceeb: 99.0% ~ 101.0%

Cov khoom muaj feem xyuam: Ib qho impurity Tsawg dua lossis sib npaug li 0.1%, tag nrho impurities Tsawg dua lossis sib npaug li 0.5%

Residual solvent: Ua raws li ICH Q3C cov qauv

Lub cev muaj zog:

Particle loj faib: D50 50-100μm

Qhov ceev: 0.4-0.6 g / cm³

Solubility: Ua tau raws li cov qauv rau cov khoom xyaw tshuaj nquag.

3. Cov ntaub ntawv ruaj ntseg:

Ntev -lub sij hawm ruaj khov: Khaws ntawm -20℃rau 24 lub hlis, txhua qhov ntsuas tau ua tau raws li qhov xav tau.

Kev ntsuas nrawm: Tom qab khaws cia ntawm 25℃rau 6 lub hlis, purity txo qis dua los yog sib npaug li 2.0%.

Kev thauj mus los ruaj khov: Kev vibration thiab poob kev xeem dhau.

Cov yam ntxwv ntawm daim ntawv thov thiab qhov zoo

1. Cov yam ntxwv ua tau zoo:

Nthuav cov leeg nqaij: Qhov tseem ceeb nce lean lub cev loj thiab cov leeg nqaij muaj zog

Kev txhim kho pob txha: Ua kom cov pob txha ceev thiab pob txha muaj zog

Txo rog: Txhawb kev rog rog thiab txhim kho lub cev muaj pes tsawg leeg

2. Cov yam ntxwv tseem ceeb thiab qhov zoo:

Tag nrho agonist: Androgen receptor tag nrho agonist, muaj zog ua haujlwm

Kev xaiv siab: siab dua selectivity rau androgen receptors dua rau lwm yam nuclear receptors.

Siv tau qhov ncauj: Siab qhov ncauj bioavailability thiab yooj yim rau siv.

3. Qhov zoo ntawm kev siv:

Yooj yim siv tshuaj: kev tswj qhov ncauj, ua rau cov neeg mob ua raws li kev cai siab.

Flexible dosage: Cov koob tshuaj tuaj yeem hloov kho raws li tus kheej cov lus teb.

Cov ntawv thov tshawb fawb: Ib qho cuab yeej zoo tshaj plaws rau kev tshawb fawb cov leeg nqaij atrophy thiab osteoporosis.

Vim li cas thiaj xaiv Suav - ua S23 ?

Muaj peev xwmagonist: Androgen receptor tiav agonist, EC 50=1 nM

Chiralkev huv: (R, R) configuration optical purity Ntau dua los yog sib npaug rau 99.8%

Tshwj xeebkev huv: Tshaj 99% siab purity, nrog kev tswj xyuas nruj.

ruaj khovmuab: Ib qho kev xa khoom tiav ua kom muaj kev xa khoom raws sij hawm thiab txhim khu kev qha.

Cov ntsiab lus

Ua nyob rau hauv Suav teb S23 raw khoom hmoovsawv cev rau qib siab - tus qauv zoo ntawm kev xaiv androgen receptor ua tiav agonists. Los ntawmadvanced chiral synthesis thev naus laus zis, kev tswj xyuas zoo, thiab cov khoom siv ruaj khov,nws muabsiab -cov cuab yeej tshawb fawb zoo heevrauKev tshawb fawb thoob ntiaj teb ntawm cov leeg nqaij atrophy thiab osteoporosis. Xaiv Ua hauv Suav teb txhais tau tias xaivkev tshawb fawb-qib zoo thiab txhim khu kev qha.

Xav taudab tsi, thov hu raupeb

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