MGF 2mg / vial Tsav Muscle Supercompensation Thiab Regeneration

MGF 2mg / lub raj mis qhia

Mechanical kev loj hlob yam|Kev kho cov leeg nqaij thiab kev loj hlob peptides 2mg / lub raj mis

Lub npe: Mechanical growth factor

English npe: MGF (Mechano Growth Factor)

Ib ntus: YQPPSTNKNTKSQRRKGSTFEEHKISNLEKERINQR

Molecular hnyav: Kwv yees li 12,000 Da

Purity: Ntau dua lossis sib npaug li 98.0% (HPLC)

Cov ntsiab lus: 2mg / lub raj mis

Qhov tshwm sim: Dawb lyophilized hmoov

Cia: khov ntawm -20 degree, tiv thaiv lub teeb, thiab khaws cia rau hauv qhov chaw qhuav.

Daim ntawv qhia kev siv thiab cia

MGF (Mechanical Growth Factor):

MGF yog qhov sib txawv ntawm cov tshuaj insulin-zoo li kev loj hlob zoo-1 (IGF-1) uas tau hais hauv zos hauv cov nqaij leeg hauv kev ntxhov siab (xws li kev cob qhia lub zog). MGF txhawb kev kho cov leeg nqaij thiab kev loj hlob los ntawm kev ua kom IGF-1 receptors, txhawb nqa satellite cell proliferation thiab sib txawv. Tsis zoo li cov txheej txheem IGF-1, MGF yog cov ntaub so ntswg tshwj xeeb, feem ntau ua rau cov leeg nqaij pob txha. Cov kev tshawb fawb soj ntsuam tau pom tias nws muaj peev xwm los txhawb cov leeg nqaij satellite cell activation, cov leeg nqaij fiber ntau hypertrophy, thiab kho kev puas tsuaj, ua rau nws muaj txiaj ntsig zoo rau kev kawm cov leeg nqaij, kev tawm dag zog, thiab kev tiv thaiv cov leeg nqaij atrophy.

Vim nws cov teebmeem tshwj xeeb ntawm cov leeg nqaij, MGF tau txais kev saib xyuas thoob plaws hauv kev tawm dag zog lub cev, kho cov leeg nqaij, thiab tiv thaiv- kev tshawb fawb txog leeg nqaij atrophy. Hauv kev sim ua qauv uas xav tau kev ntsuam xyuas ntawm cov leeg kho lub peev xwm, tom qab- qoj ib ce rov qab, thiab kho cov leeg nqaij, MGF ua haujlwm raws li cov txheej txheem tshawb fawb, muab cov kev sim hauv paus rau kev tshawb nrhiav cov leeg nqaij rov qab los thiab kev tawm dag zog.

MGF Applications:

Raws li cov leeg nqaij - tshwj xeeb kev loj hlob, nws feem ntau yog siv los kawm txog nws cov teebmeem ntawm cov leeg nqaij satellite cell ua, cov nqaij fiber ntau hypertrophy, thiab kho kev raug mob, thiab ntsuas nws txoj haujlwm tswj hwm hauv cov leeg nqaij, lub zog, thiab kev muaj peev xwm rov qab los hauv kev sim ua qauv. Nws yog ib qho cuab yeej tshawb fawb tseem ceeb rau kev tshawb nrhiav cov leeg nqaij rov tsim dua tshiab, kev tawm dag zog, thiab kev tshawb fawb los tiv thaiv - leeg nqaij atrophy.

Nws tau siv rau hauv kev tshawb fawb txog kev tawm dag zog lub cev, kev sim kho cov leeg nqaij, tiv thaiv- kev tshawb fawb cov leeg nqaij atrophy, thiab tshawb nrhiav cov leeg nqaij rov tsim dua tshiab los kawm txog lub luag haujlwm tswj hwm lub luag haujlwm ntawm MGF ntawm cov leeg loj hlob, kho, thiab rov ua haujlwm zoo raws li kev tswj hwm nruj heev.

Kev siv thiab kev khaws cia

1. Kev kho dua tshiab thiab kev npaj:

Cov kuab tshuaj pom zoo:

Nyiam cov kuab tshuaj: sterile dej rau kev txhaj tshuaj

Carrier solution:diluted nrogsterile physiological saline rau hauv vivo kev tshawb fawb.

Lus ceeb toom: Tsis txhob siv cov kua qaub los yog muaj zog alkali daws. Cov peptide no ruaj khov dua nyob rau hauv nruab nrab tej yam kev mob.

Tus txheej txheem npaj:

Solvent npaj:

Siv cov dej tsis huv rau kev txhaj tshuaj uas tau lim aseptically los ntawm 0.22 μm lim membrane.

Qhov ntsuas kub hnyav tau rov qab los rau hauv chav sov (20-25 degree).

Reconstitution txheej txheem:

Ntxiv 1.0 mL dej sterile rau txhaj rau 2 mg vial.

Ncuav maj mam raws lub raj mis phab ntsa kom tsis txhob cuam tshuam ncaj qha rau cov hmoov.

Maj mam tig lub vial rau 3-5 feeb kom txog thaum yaj tag thiab cov tshuaj ua kom meej.

Qhov kawg concentration: 2 mg / mL.

Dispensing thiab dilution:

Tam sim ntawd muab tso rau hauv ib zaug - siv koob tshuaj 20-50 μL siv cov tshuaj qis qis qis.

Dilute nrog sterile saline mus rau qhov yuav tsum tau ua hauj lwm concentration.

Kom meej meej daim ntawv lo: lub npe, concentration, npaj hnub, batch naj npawb, thiab cia tej yam kev mob.

Ua hauj lwm concentration/dosage reference:

Kev sim hauv vitro: Feem ntau siv cov concentration ntau yog 10 ng / mL txog 1 ug / mL, thiab cov kev sim ua ntej yuav tsum tau ua kom ua kom zoo dua qhov concentration raws li qhov kev sim tshwj xeeb.

Tsiaj sim:

Hauv zos intramuscular txhaj: Qhov ntau npaum li cas yog 10 txog 100 ug / qhov chaw.

Kev txhaj tshuaj subcutaneous: Qhov koob tshuaj ib txwm yog 0.1 txog 1 mg / kg.

Nws raug pom zootias cov koob tshuaj meej meej raug txiav txim raws li tus qauv tsiaj tshwj xeeb, txoj hauv kev ntawm kev tswj hwm, cov hom phiaj tshawb fawb, thiab cov ntaub ntawv luam tawm.

Piv txwv ntawm kev npaj xam: Yog tias xav tau 100 ug / mL cov tshuaj ua haujlwm, noj 0.05 mL ntawm cov tshuaj hauv Tshuag thiab ntxiv rau 0.95 mL ntawm physiological saline.

Cov ntsiab lus tseem ceeb kom nco ntsoov:

Cov txheej txheem nruj aseptic: Ua haujlwm hauv lub rooj zaum huv si thiab siv cov khoom siv tsis muaj menyuam, tshwj xeeb tshaj yog thaum siv tshuaj hauv vivo.

Zam lub teeb: Nws yog rhiab heev rau lub teeb, yog li nws raug pom zoo kom ua haujlwm hauv qhov chaw tsaus.

Npaj thiab siv tam sim ntawd: Tom qab kev kho dua tshiab, nws yuav tsum siv li ntawm 24 teev. Tom qab muab tshuaj, cia nyob rau hauv cov kev cai teev tseg.

Tsis txhob adsorption: Siv silanized qis- cov raj adsorption tuaj yeem txo cov adsorption poob ntawm phab ntsa raj.

2. Cia tej yam kev mob:

Unreconstituted lyophilized hmoov:

Ntev - lub sij hawm cia: khov ntawm -20 degree, txee lub neej 24 lub hlis.

Kev cia zoo: -80℃tob khov, txee lub neej 36 lub hlis.

Kev tiv thaiv nruj ntawm lub teeb: Yuav tsum muab khaws cia rau hauv lub teeb qub- pov thawj aluminium foil hnab.

Kev tiv thaiv noo noo: Khaws qhuav; muaj desiccant.

Reconstituted daws:

Siv tam sim ntawd: Rau kev ua haujlwm zoo tshaj plaws, siv tam sim tom qab hloov kho.

Short - lub sij hawm cia: Txias ntawm 2-8℃deb ntawm lub teeb, tsis pub ntau tshaj 24 teev.

Repackage thiab khov: Khaws ntawm -20℃lossis -80℃deb ntawm lub teeb tsis pub ntau tshaj 72 teev.

Rov qab khov-thaw cycles raug txwv nruj heev: qhov siab tshaj plaws ntawm ib qho khov -thaw voj voog.

Kev thauj mus los:

Txias- cov hmoov qhuav: thauj los ntawm cov dej khov qhuav (-78 degree).

Luv - lub sij hawm shipping: 2-8℃ice pob shipping, xyuas kom tus me nyuam tsis pub dhau 48 teev.

3. Kev ruaj ntseg thiab cov qauv ua tiav:

Tshuaj thiab lub cev stability:

Nws yog qhov ruaj khov hauv nruab nrab pH aqueous daws.

Tsis txhob sib cuag nrog cov kua qaub uas muaj zog, muaj zog alkalis, thiab oxidizing tus neeg sawv cev.

Nws yog rhiab heev rau qhov kub thiab txias, yog li tsis tshua muaj - qhov kub thiab txias cia tau pom zoo.

Kev kho ntawm bioactivity:

Kev khaws cia kom zoo thiab cov txheej txheem npaj tsim nyog yog qhov tseem ceeb rau kev tuav haujlwm.

Txhawm rau kom tsis txhob rov khov dua -thaw cycles, nws raug nquahu kom khaws cov ntsiab lus hauv qhov me me.

Xav taudab tsi, thov hu raupeb

Cim npe nrov: mgf 2mg / vial drives leeg supercompensation thiab regeneration, Tuam Tshoj mgf 2mg / vial drives leeg supercompensation thiab regeneration manufacturers, lwm tus neeg, Hoobkas