GHK-CU 50mg/vial Nws txhawb nqa kev sib txuas ntawm Collagen, Elastin, thiab Glycosaminoglycans.

GHK-Cu Copper Peptide 50mg/bottle Core Taw qhia

Tripeptide Copper Complex|Qhov tseem ceeb tshaj plaws rau kev kho cov ntaub so ntswg thiab tiv thaiv -Kev laus 50mg / lub raj mis

Lub npeGlycylhistyllysine tooj liab complex

Ib ntus: Gly-Nws-Lys-Cu²⁺

Molecular hnyav: kwv yees 340.8 Da

Purity: Ntau dua lossis sib npaug li 98.5% (HPLC)

Qhov tshwm sim: Blue lyophilized hmoov

Cia: Txias ntawm 2-8 degree, deb ntawm lub teeb thiab khaws cia rau hauv qhov chaw qhuav.

Daim ntawv qhia kev siv thiab cia

GHK-Cu tooj liab peptide:

GHK-Cu yog ib qho tshwm sim ntawm tooj liab- ion tripeptide complex thiab ib qho tseem ceeb taw qhia molecule hauv tib neeg lub qhov txhab kho thiab tiv thaiv- txheej txheem kev laus. Tsis zoo li cov khoom siv hluavtaws, nws muaj nyob hauv tib neeg cov ntshav plasma, nrog cov concentrations tsawg zuj zus nrog lub hnub nyoog. Los ntawm kev sib koom ua ke ntawm tooj liab ions, GHK-Cu siv ntau yam kev kho thiab rov tsim dua tshiab ntawm cov qib cellular thiab molecular, nrog rau kev txhawb nqa collagen synthesis, txhawb kev angiogenesis, tswj cov lus teb inflammatory, thiab ua rau muaj kev cuam tshuam antioxidant. Nws cov khoom siv ua haujlwm tshwj xeeb ua rau nws muaj txiaj ntsig zoo hauv kev tshawb fawb ntawm daim tawv nqaij, kho qhov txhab, thiab cov ntaub so ntswg engineering.

Vim nws zoo heev kho cov ntaub so ntswg thiab tiv thaiv - inflammatory zog, GHK-Cu yog nyiam los ntawm ntau cov kws tshawb fawb nyob rau hauv daim tawv nqaij regeneration thiab cov ntaub so ntswg kho. Nws tsis ua los ntawm cov tshuaj hormones receptors, tab sis ncaj qha txhawb nqa kev hloov pauv ntawm cov cellular matrix los ntawm kev ua kom muaj cov noob qhia tshwj xeeb thiab cov kev taw qhia. Nws kho cov txheej txheem maj mam thiab muaj peev xwm rov tsim dua tshiab hauv ntau cov ntaub so ntswg, suav nrog daim tawv nqaij, plaub hau, thiab cov hlab ntsha, ua rau nws yog ib qho cuab yeej zoo tshaj plaws rau kev kawm ntawm daim tawv nqaij laus, kho qhov txhab mob, thiab tshuaj kho kom zoo nkauj.

Kev siv ntawm GHK-Cu copper peptides:

Nws txhawb nqa collagen thiab elastin synthesis, txhim kho cov ntaub so ntswg thiab rov tsim dua tshiab, thiab muaj cov haujlwm tseem ceeb antioxidant. GHK-Cu yog lub ntuj qhia peptide raws li bioactivity ntawm tooj liab ions, ua lub luag haujlwm tseem ceeb hauv kev rov ua dua tshiab ntawm tes thiab hloov kho matrix.

GHK-Cu yog dav siv hauv vitro thiab preclinical kev tshawb fawb txog cov tawv nqaij rov tsim dua tshiab, kho qhov txhab, thiab tiv thaiv -aging. Nws txoj kev txhawb nqa ncaj qha ntawm ntau hom cell, suav nrog fibroblasts thiab keratinocytes, txhawb kev kho cov ntaub so ntswg zoo yam tsis muaj kev pheej hmoo loj hlob cuam tshuam nrog kev loj hlob ib txwm muaj. Yog li ntawd, GHK-Cu muab cov qauv kev tshawb fawb muaj txiaj ntsig zoo thiab nyab xeeb rau kev tshawb nrhiav cov txheej txheem kho qhov txhab, tiv thaiv- cov tswv yim kho kev laus, thiab tsim cov ntaub so ntswg engineering technologies.

Txoj kev siv thiab khaws cia

1. Kev kho dua tshiab thiab kev npaj:

Cov kuab tshuaj pom zoo:

Nyiam cov kuab tshuaj: sterile dej rau kev txhaj tshuajlos yogphysiological saline (0.9% NaCl)

Kev ruaj ntseg optimization: Sterile dej muaj 1% sodium hyaluronate(rau kev tshawb fawb siv tshuaj pleev ib ce)

Rau kev sim ntawm tes: Dissolve hauv dej tsis muaj menyuam thiab tom qab ntawd dilute nrog cov ntshav qab zib -dawb kab lis kev cai nruab nrab.

Cov kev ceev faj: Tsis txhob siv dej nrog cov ntsiab lus hlau ion siab lossis cov tshuaj tsis haum uas muaj EDTA.

Tus txheej txheem npaj:

Solvent npaj:

Cov kuab tshuaj tau sterile lim los ntawm 0.22 μm lim membrane.

Rov qab cov kuab tshuaj mus rau hauv chav tsev kub (20-25 degree) kom tsis txhob overheating.

Reconstitution txheej txheem:

Ntxiv 1.0-2.0 mL ntawm cov kuab tshuaj pom zoo rau 50 mg vial.

Maj mam hliv cov kua rau sab ntawm lub raj mis, maj mam tig lub raj mis kom nws yaj.

Tom qab dissolution, nws yuav tsum yog ib tug ntshiab xiav tov.

Cov lus pom zoo: 25-50 mg / mL

Dispensing thiab dilution:

Tam sim ntawd muab tso rau hauv qhov tsaus ntuj -xim lossis lub teeb- tiv thaiv, qis- nqus centrifuge raj.

Dilute mus rau qhov ua haujlwm concentration nrog cov tshuaj tsis haum raws li kev xav tau ntawm kev sim.

Clear labeling: Khoom npe, concentration, hnub npaj

Ua haujlwm concentration siv:

Kev sim hauv vitro cell: Feem ntau siv ua haujlwm concentration ntau yog 1 nM txog 10 μM

Kev tshawb fawb txog kev thov: 0.1% mus rau 1.5% daws

Kev tshawb fawb tsiaj: Kev siv ntau npaum li cas yog 0.1 txog 2 mg / kg / hnub

Piv txwv ntawm kev npaj xam: Yog tias xav tau 1mM cov tshuaj ua haujlwm, noj li 3.4μL ntawm 50mg / mL cov tshuaj npaj thiab ntxiv rau 1mL ntawm kab lis kev cai nruab nrab (molecular hnyav txog 341g / mol).

Cov ntsiab lus tseem ceeb kom nco ntsoov:

Lub teeb rhiab heev: GHK-Cu yog lub teeb rhiab heev, thiab txhua txoj haujlwm yuav tsum tau ua nyob rau hauv lub teeb nruj- cov ntaub ntawv pov thawj.

Hlau paug: Tsis txhob sib cuag nrog cov cuab yeej hlau thiab ua qhov tseem ceeb ntawm kev siv cov khoom siv yas.

Solubility: Solubles zoo nyob rau hauv sterile dej, tsim ib tug ntshiab xiav tov. Yog tias dissolution nyuaj, maj mam vortex.

Kev ua haujlwm aseptic: nruj me ntsis ua nyob rau hauv lub laminar flow hood.

Npaj thiab siv tam sim ntawd: Qhov kev ruaj ntseg ntawm cov tshuaj yog txwv tom qab reconstitution, yog li nws raug pom zoo kom siv nws sai li sai tau.

2. Cia tej yam kev mob:

Unreconstituted lyophilized hmoov:

Short - lub sij hawm cia: Txias ntawm 2-8 degree, txee lub neej 12 lub hlis.

Ntev - lub sij hawm cia: khov ntawm -20 degree, txee lub neej 24 lub hlis.

Kev tiv thaiv nruj ntawm lub teeb: Yuav tsum muab khaws cia rau hauv lub teeb qub- pov thawj aluminium foil hnab.

Kev tiv thaiv noo noo: Khaws qhuav; muaj desiccant.

Reconstituted daws:

Siv tam sim ntawd: Rau kev ua haujlwm zoo tshaj plaws, siv tam sim tom qab hloov kho.

Short - lub sij hawm cia: Khaws ntawm 2-8℃deb ntawm lub teeb tsis pub ntau tshaj 24 teev.

Repackage thiab khov: Khaws ntawm -20℃deb ntawm lub teeb tsis pub tshaj 7 hnub.

Rov qab khov-thaw cycles raug txwv nruj heev: qhov siab tshaj plaws ntawm 1-2 lub voj voog khov-thaw tau tso cai.

Kev thauj mus los:

Lub tub yees thauj: Kev thauj mus los nrog cov ntim dej khov ntawm 2-8 degree.

Txias- cov hmoov qhuav qhuav: Nws tuaj yeem thauj tau ntawm chav tsev kub, tab sis lub tub yees tau pom zoo kom muaj kev ruaj ntseg zoo.

Ntim: Lub teeb- pov thawj aluminium foil hnab + lub tshuab nqus tsev foob + ua npuas ncauj insulated lub thawv.

3. Kev ruaj ntseg thiab cov qauv ua tiav:

Tshuaj stability:

Nws yog qhov ruaj khov tshaj plaws hauv cov tshuaj aqueous nrog pH ntawm 6.0-7.5.

Cov kua qaub muaj zog, cov hauv paus muaj zog, lossis cov oxidizing muaj zog tuaj yeem rhuav tshem nws cov qauv.

Nws yog rhiab heev rau qee cov hlau ions thiab tuaj yeem hloov pauv ligand.

Lub cev thiab optical stability:

Cov tshuaj yog rhiab heev rau lub teeb (tshwj xeeb tshaj yog ultraviolet lub teeb), thiab nws cov xim yuav lighten.

Tsis txhob kub siab, ua nruj ua tsiv, thiab kho ultrasonic.

Xav taudab tsi, thov hu raupeb

Cim npe nrov: ghk-cu 50mg / vial nws zoo txhawb kev sib txuas ntawm collagen, elastin, thiab glycosaminoglycans., Tuam Tshoj ghk-cu 50mg / vial nws zoo txhawb kev sib txuas ntawm collagen, elastin, thiab glycosaminoglycans. manufacturers, lwm tus neeg, Hoobkas