Vilon® 20mg / lub raj mis qhia
Pharmaceutical -qib thymopeptide|Ua nyob rau hauv Tuam Tshoj immunomodulatory peptide 20mg / lub raj mis
Amino acid ua ntu zus: Lys-Glu
CAS Nr.: 34346-22-0
Molecular hnyav275.3 Nws
Purity: Ntau dua lossis sib npaug li 99.0% (HPLC kuaj pom)
Qhov tshwm sim: Dawb lyophilized hmoov
Cia: Khaws khov ntawm -20℃deb ntawm lub teeb; Tom qab thawing, refrigerate ntawm 2-8 degrees.
Core zoo thiab muaj nuj nqi
Vilon® yog ibdipeptide yog tsim los ntawm lysine thiab glutamate, thiab yogqhov luv tshaj active fragment ntawm tsev neeg thymosin. Nws yog Ameslikas cais los ntawm thymus extract. Los ntawmregulating T cell muaj nuj nqi, pab txhawb kev tiv thaiv kab mob, rov ua kom lub cev tiv thaiv homeostasis, thiab ncua kev tiv thaiv kab mob., nws muaj nuj nqis tseem ceeb hauv cov teb ntawmKev tswj kev tiv thaiv kab mob, tiv thaiv- kev laus, kev tiv thaiv kab mob, thiab kev tshawb fawb txog kab mob autoimmune . Nws yog ib qho tseem ceeb ntawm cov cuab yeej molecule hauv immunopharmacology thiab kev laus immunology tshawb fawb.
✅CoreMechanism ntawm Action:
T cell kev cai: Txhawb T lymphocyte sib txawv thiab kev loj hlob, thiab tswj cov CD4+/CD8+ piv.
Kev tiv thaiv kab mob: Txhim kho NK cell kev ua haujlwm thiab txhim kho kev tiv thaiv kev tiv thaiv kev ua haujlwm.
Thymus regeneration: Stimulates thymic epithelial hlwb thiab qeeb thymus degeneration.
Anti-cov teebmeem kev laus: Txo cov hnub nyoog- cuam tshuam txog kev tiv thaiv kab mob tsis muaj zog thiab rov qab tiv thaiv kab mob.
Antioxidant tiv thaiv: Tshem tawm cov dawb radicals thiab txo oxidative puas tsuaj rau lub cev tiv thaiv kab mob.
Kev tiv thaiv - kev tswj hwm kev mob: ntsuas qhov pro-inflammatory/anti-inflammatory cytokine network
✅Qualityqhov zoo ntawm Suav manufacturers:
Synthesis txheej txheem: Fmoc solid-theem synthesis method tau txais yuav, ua ke nrog cov kua chromatography purification.
Kev tswj kom zoo: Rov qab-theem HPLC purity Ntau dua lossis sib npaug li 99.0%, chiral purity Ntau dua lossis sib npaug li 99.5%.
Cov qauv kev pom zoo: Dual kev pom zoo los ntawm huab hwm coj spectrometry thiab nuclear magnetic resonance
Kev ua validation: Hauv vitro T cell proliferation sim + hauv vivo immune qauv validation
Kev tiv thaiv aseptic: Chav Kawm C cleanroom, 0.22μm sterile filtration
Kev ruaj ntseg: Ntev-Kev kawm ruaj khov ua tiav (-20 degree, 24 lub hlis)
✅ khoomNta:
Me me molecular hnyav: yooj yim absorbed, siab bioavailability
Zoo stability: Lub khov- cov hmoov qhuav qhuav yog ruaj khov.
High kev ruaj ntseg profile: tsis muaj cytotoxicity, dav kho qhov rais
Synergistic nyhuv: tuaj yeem siv ua ke nrog thymopentin, thymosin 1, thiab lwm yam.
Daim ntawv qhia kev siv thiab cia
1. Kev kho dua tshiab thiab kev npaj:
Cov kuab tshuaj pom zoo:
Kev sim hauv vitro:sterile PBS tsis(pH 7.2-7.4)
Hauv kev tshawb nrhiav vivo:sterile saline
Cell kab lis kev cai:ntshav qab zib -dawb RPMI-1640 nruab nrab
Daim ntawv thov tshwj xeeb:physiological saline muaj 0.1% BSA
Txheem configuration:
Ncuav 2 mL ntawm cov kuab tshuaj rau hauv 20 mg vial thiab maj mam swirl kom yaj.
Ib qho kev daws teeb meem ntawm10 mg/mlua tau.
Dilute mus ua hauj lwm concentration nrog kab lis kev cai nruab nrab los yog tsis.
Cov ntsiab lus npaj:
Lub sij hawm dissolving: 3-5 feeb ntawm chav tsev kub
Cov txheej txheem soj ntsuam: ntshiab thiab pob tshab, tsis muaj cov khoom
Dilution txheej txheem: Dilute maj mam kom tsis txhob ncaj qha siab concentration.
Contraindications: Tsis txhob muaj zog acids, muaj zog alkalis, thiab oxidizing tus neeg sawv cev.
2. Cia tej yam kev mob:
Tsis qhib:
Cia txias ntawm -20 degree:24 hli
-80℃sib sib zog nqus khov:36 muaj
Tsis txhob rov khov dua -thaw cycles (tsawg dua lossis sib npaug li 3 zaug).
Rov tsim dua:
Kev daws teeb meem: Txias ntawm 4℃thiab sivhauv 7 hnub.
Kev daws teeb meem ua haujlwm:Npaj tshiab thiab siv tam sim ntawd; tsis pub tshaj 24 teev ntawm 4 degree.
Rov ntim dua thiab khaws cia rau hauv qhov me me kom tsis txhob kis kab mob.
Kev thauj mus los:
Kev thauj mus los txias (hauv qab -20 degree)
Kev thauj dej khov qhuav (ntev -tsheb thauj mus los)
Cov ntaub ntawv ntsuas kub
Stability parameters:
Kub: ruaj khov hauv qab -20 degree
Lub teeb raug: Khaws deb ntawm lub teeb.
Humidity: txheeb ze humidity <60%
Stable ntawm pH 6.0-7.5
Vim li cas thiaj xaiv Vilon® ua hauv Suav teb?
Technicalqhov zoo:
Professional peptide synthesis ntau lawm kab
Ib qhov zoo-chaw kuaj xyuas kev tswj xyuas zoo
Muaj kev paub dhau los hauv kev tshawb fawb immunology
Ua tau raws li cov qauv zoo thoob ntiaj teb
Zoolav:
HPLC purity Ntau dua lossis sib npaug li 99.0%
Cov amino acid muaj pes tsawg leeg yog 100% ua raws.
Endotoxin<1.0 EU/mg
Dhau qhov kuaj tsis muaj menyuam
Cov hlau hnyav<10 ppm
Cov dej noo <5.0%
Cov ntsiab lus
Vilon®, ibQhov luv tshaj active thymosin fragment, tuav tus nqi tshwj xeeb hauvcov teb ntawm immunomodulation thiab tiv thaiv- kev tshawb fawb kev laus. Cov chaw tsim khoom hauv Suav teb muab cov kws tshawb fawbib lub siab -zoo, muaj zog tshawb nrhiav cov cuab yeej los ntawm kev tswj xyuas kom zoo thiab kev ua tiav kev ua tiav. Cov yam ntxwv ntawm immunomodulatoryntawm cov khoom no muab cov ntsiab lus tseem ceeb rau kev tshawb fawb thiab kev cuam tshuam ntawm kev tiv thaiv kab mob -txog kab mob.
Xav taudab tsi, thov hu raupeb
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