Hauj lwm lawm

Kev tsis

Gonarelin 2mg / BUTY CORN COG LUS

Kws muag tshuaj - beet peptide cov qauv txheej txheem|Gonadorelin, ua nyob rau hauv Suav teb

Tshuaj lom neeg npe: Pyroplutamyl -}}}}-} tryl {} {3 tyros yl - glycyl {{5 5}} lucyl {}}}} prgyl {}} glycamide

Muaj kab muaj kev: pglu - nws-}}}}}} gly- nh₂

Cas tsis muaj.: 33515-09-2

Kev qhia tshwj xeeb: 2mg / lub raj mis

Ntse Dosage Daim Ntawv: Lyophilized hmoov rau kev txhaj tshuaj

Molecular Cov Qauv: C₅₅H₇₅N₁₇O₁₃

Molecular hnyav: 1182.3

Kev tshwm sim: Dawb khov -}} qhuav lumpy hmoov

Kev coj dawb huv: Ntau dua los yog sib npaug rau 98% (hplc Nrhiav tau)

Kev Cia: Khw ntawm 2-8℃deb ntawm lub teeb.

Cov teebmeem tseem ceeb

Gonarelin yog aGonadotropin - tso cov hormone (gnrh)uas tau siv dav rauhypothalamic- pituitary - gonadal kho kab, kev tshawb fawb muaj zog, thiab endocrrine kev tshawb nrhiavVim nwsdecaptide qauv uas tau zoo ib yam li endogenous gnrh.

✅ Mem Tes Tes Plaub Tes Ua Tsheb:

Pituitary Jimulation: Txhawb kev tso tawm Luteinizing huteinizing hormone (lh) thiab follicle -}}}}}}}}}) los ntawm lub caj dab anterior piduitary.

Mem tes -} kav: Pulse -} Raws cov khoom siv tshuaj yuav mimic physiological gnrh tso zais.

Cov Kev Cai Tswj Gonadal: Tsis ncaj ncees tswj hwm cov synthesis ntawm testosterone thiab estrogen.

Sib haisQhov Zoo Ntawm Suav Raug:

Purity guaranteed: Cov khoom {-} theem ntau yam xwm txheej, kev coj dawb huv ntau dua lossis sib npaug ntawm 98%, ib qho kev cuam tshuam rau 0.1%.

Sab Nrauv Qhov tseeb: Daim ntawv txiav txim siab yog 100% raug.

Kev Ua Kom Zoo: Nyob rau hauv vitro lh tso tawm ec50 <0.1 nm

✅globalmuab kev lees paub:

Cov Khoom Siv Txias Txias: 2-8 Degree Txias chanport thoob plaws tag nrho cov txheej txheem los xyuas kom cov khoom ruaj khov.

Zov -} wareyhouse khoom xa: Cov chaw khaws khoom hauv cheeb tsam muaj nyob hauv Suav teb, Tebchaws Europe, Amelikas, thiab Asia - pacific cheeb tsam, kom cov khoom xa tuaj tsis pub dhau 7 hnub.

Txhawb Nqa Kev Pab Cuam Kev Lis Haujlwm: Kev npaj cov ntaub ntawv tshaj lij du cov kev lis kev cai tshem tawm thoob ntiaj teb.

Cov Txheej Txheem Ntau Lawm thiab Kev Ntsuas Zoo

1. Advances Prestisis Txheej Txheem:

Cov khoom -} theem txheej txheem synthesis: The Fmoc solid-phase synthesis strategy was adopted, with a condensation efficiency >99.5%.

Tus Txheej Txheem Purification: Npaj HPLC muaj kev ua kom huv, gradient elove, sau los ntawm lub ncov siab.

Khov -}} qhuav technology: kub {- mte maub khov khov {}}}}}} moist moist moist moist် ntsiab lus tsawg dua los yog sib npaug rau 3.0%.

2. Nruj metric qauv tswj hwm:

Tshuaj lom neeg purity:

Cov ntsiab lus tseem ceeb: 98.0% ~ 102.0%

Related tshuaj: ib leeg los ntawm 0.1%, tag nrho cov impurities tsawg dua los yog sib npaug rau 0.5%

Acetic acid cov ntsiab lus: tsawg dua los yog sib npaug rau 10.0% (ion chromatography)

Kev ua haujlwm biological:

Hauv vitro lh tso tawm Assay: potency tsis tsawg dua 90% ntawm tus qauv.

Hauv vivo bioassays: Ntsib Pharmacopoeia cov qauv

3. Cov ntaub ntawv ruaj khov:

Ntev -} lub sij hawm ruaj khov: Khaws cia ntawm 2-8℃rau 24 lub hlis, txhua qhov ntsuas tau raws li qhov yuav tsum tau ua.

Nrig kuaj ntsuas: Tom qab tau khaws cia ntawm 25℃rau 6 lub hlis, lub purity txo qis dua los yog sib npaug rau 2.0%.

Ruaj: Tom qab rov kho dua tshiab, khaws cia ntawm 2-8℃rau 24 teev; Purity ntau dua los yog sib npaug rau 95%.

Kev Tshawb Fawb Kev Tshawb Fawb thiab Kev Tshawb Xyuas Kev Tshawb Fawb

1. Mechanism ntawm kev kawm:

Receptor binding: Khi nrog high affinity rau pituitary gnrh recept (kd =0.1 nm)

Kev Hloov Chaw: Ua kom cov phospholholase C Txoj kev phoswhipase, txhawb nqa synthesis thiab tso ntawm LH thiab FSH.

Mem tes cov yam ntxwv: Pulse {-} Raws cov khoom siv tshuaj yuav zam kev receptor desensitization.

2. Kev Tshawb Fawb thiab Cov Chaw Thov:

Muaj me nyuam tshuaj: Kev kuaj mob thiab kev kho mob ntawm Hypothalamic Amenorrhea thiab ntxiv lawm tshob

Endocrinology: Kev ntsuas ntawm hypothalamic - pituitary - gonadal axis muaj nuj nqi

Veterinary Tshuaj: Cov Kev Txiaj Ntsig Rau Tsiaj thiab Estrus Kev Tswj Xyuas

3. Preformical cov ntaub ntawv:

Lh tso tawm: Nrawm nrawm nrawm tom qab txhaj tshuaj, ncav cuag cov qib peak hauv 30 feeb.

Fsh tso tawm: Txhawb FSH Secromion, nrog tus yam ntxwv me dua LH.

Pulsed Administration: Cov tswj hwm pulsed tuaj yeem tswj hwm cov kev ua haujlwm zoo li qub.

Tuam Tshoj cov khoom lag luam zoo zoo

1. Cov txiaj ntsig zoo hauv kev tsim cov txheej txheem:

Khoom siv thev naus laus zis: Microwave - pab tau cov khoom - Lub xeev synthesis nrog kev ua hluav taws xob siab.

Tus Txheej Txheem Purification: Npaj HPLC ua kom huv siab, muaj kev ceev siab ntau dua lossis sib npaug rau 98%.

Kev Tswj Xyuas Zoo: Kev tswj hwm zoo thoob plaws tag nrho cov txheej txheem los ntawm cov khoom raw ua tiav cov khoom tiav.

2. Cov Lus Qhia Zoo:

Raws li cov qauv: Ua tau raws li cov kws muag tshuaj Suav, USP, thiab EP cov qauv.

Kev kawm ruaj khov: Ua tiav cov kev tshawb nrhiav ruaj khov.

Batch sib xws: Cov txheej txheem nruj tswj xyuas kom ua tiav kev sib xws ntawm cov khoom.

3. Cov Khoom Siv Hauv Ntiaj Teb:

Ntau lawm lub hauv paus: GMP -}} ua tiav ntau lawm hauv paus hauv Suav teb

Distribution network: Lub chaw xa khoom thoob ntiaj teb thiab cov khoom xa tuaj txias

Kev Sau Npe: Txhawb kev sau npe cov ntawv thov los ntawm cov teb chaws thoob ntiaj teb.

Vim li cas thiaj xaiv Gonaraylin Ua hauv Suav teb?

Yam xwm txheejkev ua yog: Cov kev txiav txim siab decapeide yog 100% yog thiab ua raws li Endogenous Gnrh.

Siabkev coj dawb huv: Hla 98% kev coj dawb huv, nrog kev tswj nruj me ntsis.

Mem tesCov yam ntxwv: Pulse {-} Raws cov khoom siv tshuaj yuav zam kev receptor desensitization.

Lub nkuajmov: Ib qho kev ua tiav muab saw ua kom tiav thiab txhim khu kev qha.

Lub ntsiab

Ua nyob rau hauv Suav teb, gonarelin 2mg Lyophilized hmoov rau kev txhaj tshuajsawv cev qhov siab - zoo qauv ntawm gonadotropin - tso cov hormoneCov. DhauAdvanced synthesis cov txheej txheem, nyuaj tswj, thiab lub zog ruaj khov,Nws muabhigh - Zoo, Heev Cov Cuab Yeej Tshawb FawbrauKev Tshawb Fawb thiab itocrinology Kev Tshawb Nrhiav Thoob Ntiaj Teb Thoob Ntiaj TebCov. Xaiv ua nyob rau hauv Suav teb txhais tau tias xaivKev Tshawb Fawb - qeb Qib zoo thiab txhim khu kev qha ntawv lees paub.

Xav taudab tsi, thov hu raupeb