Hauj lwm lawm

Kev tsis

5 - amino-1mq (5-amino-1-Methylquinomine) 5mg / Lub Tog Zaum Core Cart

Kev Tshawb Nrhiav {{{}}}} grade gradeilized hmoov|Nnmt enzyme inhibitor (nicotinamide n - methyluratorase inhibitor)

Tshuaj lom neeg npe: 5-amino-1-Methylquinine

Cas tsis muaj.: **7151-27-7

Molecular cov mis: c₁₀h₁₀n₂

Molecular hnyav: 158.20

Purity: ntau dua los yog sib npaug rau 98% (HPLC)

Cov Lus Qhia Tshwj Xeeb: 5mg / Lub raj mis

Tsos: dawb kom tawm - dawb khov -} qhuav hmoov

Kaus: 1ML Cov Dej 1ML Bacteriostatic

Cov teebmeem tseem ceeb

5-amino-1-Methylquinoline (5-amino-1mq) yog amuaj zog thiab xaiv nicotinamide n - methyltransferase (NNMT) inhibitorCov. Vim nwsCov kev cai metabolic thiab anti -}} aging cov yam ntxwv, nws yog dav sivHauv Kev Tshawb Xyuas Kab Mob Me Meatolic, anti {-} Kev Cuam Tshuam, thiab Kev Cai Loj Me Me.

✅ Nnmt enzyme special inhibition:

Inhibits nicotinamide n - methyltransferte, thaiv cov kev hloov pauv ntawm nicotinamide (nam) rau 1-methylnicotinamide (1-Mnam)

Nce intracellular nad + qibthiab txhim kho tes metabolism hauv lub zog

✅ Cov nyhuv metabolic reprroogramming:

Txhim kho cov insulin rhiabthiab txhawb nqa cov roj metabolism

Txo cov roj zuj zusthiab tiv thaiv kev rog rog -}}} Cov metabolic cuam tshuam

✅ Anti -} kev laus peev xwm:

Qhib Sirtuins Ntev Ntev Proteinskom ncua kev laus ntawm tes

Txhim khu mitochondrial muaj nuj nqiThiab txhim kho lub hnub nyoog -}}} Edel ntsig txog kev poob qis

✅ Qhov Zoo:

Siab heev xaivthiab tshwj xeeb cov phiaj xwm nnmt enzyme

Siab qhov ncauj bioavailability, yooj yim los tswj

Kawg Cov Khoom Qhia Khoom Siv Khoom Taw Qhia

1. Kev npaj ntawm kev txhaj tshuaj (5 mg / ml):

Daim ntawv qhia piv txwv(Ua 10 fwj):

5-amino-1mq raw khoom: 50mg

Saline li qub: ntxiv rau 10ml

Npaj txheej txheem:

Cov Khoom Siv Raw Kev Ua Si: DUAB nyob rau hauv cov ntsev qub, zam kev nplawm

PHOONATION: Siv Dilute Hydrochloric acid los yog sodium hydroxide kom kho cov pH rau 6.0-7.5

Kev ua kom tsis muaj neeg lim: 0.22μm membrane kev kub siab ua siab kub siab

Ntim thiab Nitrogen Sau: ntim hauv qab ib puag ncig tsis muaj menyuam, nitrogen puv

Kev Tswj Xyuas Zoo:

Assay: HPLC Txuj Ci, cov ntsiab lus yuav tsum 95% -105% ntawm cov nqi

Lwm yam tshuaj: Ib leeg impurity tsawg dua los yog sib npaug rau 0.5%, tag nrho cov impurities tsawg dua los yog sib npaug rau 1.0%

Xeem: Ua Raws Pharmacopoia Cov Cai

2. Npaj sau ntawv:

Zam kev ua haujlwm lub teeb: nkag siab lub teeb, xav tau kev lag luam hauv qhov tsaus ntuj

Tswj Qhov Kub: Kev ua haujlwm kub tsawg thoob plaws hauv cov txheej txheem (2-8 Degree)

Kev ruaj khov: siv tsis pub dhau 4 teev tom qab rov kho dua tshiab

Cov kev siv raws tu qauv

1. Txhaj tshuaj:

Txhaj Tshuaj Tiv Thaiv:

Dosage: 1-5 Mg / kg ib zaug txhua hnub

Hnyav: Physiological Saline lossis PBS Tsis

Enavenusous txhaj:

Dosage: 0.5-2 mg / kg ib zaug txhua hnub

Kaus: cov saline li qub, maj mam thawb (tsis tsawg dua 5 feeb)

2. Kev Xaiv Kho Mob:

Kev Tshawb Fawb Kab Mob Kev Tshawb Fawb:

Kev pham cov qauv: 2-5 mg / kg / hnub, intraperStendoneal txhaj, 4-8 lub lis piam

Kab Mob Ntshav Qab Zib Cov Qauv: 1-3 mg / kg / hnub, kev txhaj tshuaj tiv thaiv, 2-4 lub lis piam

Anti -}} kev tshawb fawb:

Kev laus qauv: 1 {- 2 mg / kg / hnub, intraperatitoneal txhaj tshuaj, kev cuam tshuam ntev

Cov tshuaj yuav tsum tau hloov kho raws li cov qauv tshwj xeeb

3. Kev tiv thaiv rau kev siv:

Siv tam sim ntawd tom qab dissolving, kev daws teeb meem tsis ruaj khov

Khw kom deb ntawm lub teebTxhawm rau tiv thaiv kev ua kom muaj kev cuam tshuam

Qee cov tsiaj tej zaum yuav muaj kev ntxhov siabthiab yuav tsum tau saib xyuas kom zoo.

Vim li cas thiaj xaiv 5-amino-1mq?

Thawj nnmt enzyme inhibitor, tsom mus rau txoj kev tshiab rau cov teeb meem metabolic

Txhawb Nad + qibthiab muab ntau yam anti -} kev pab cuam laus

Txhim Kho Kev Noj Qab Haus Huv Metabolic, cov cuab yeej tshiab rau kev rog thiab cov kev tshawb fawb ntshav qab zib

Kev Muaj Peev Xwm Zoo:

GMP -} ua tiav ntau lawm, txhua pobHPLC Purity kuaj (loj dua lossis sib npaug rau 98%)

Thib peb - tog kab ke ceeb toom (COA)suav nrog cov khoom

Microbial txwv kuajTxhawm rau kom muaj kev nyab xeeb

Lub Ntiaj Teb Shipping:

Kho Mob Vial Ntim, roj hmab nres foob

Kev thauj mus los txias(2-8 degree) kom ntseeg tau cov khoom ruaj khov

Ntiav neeg, tsis muaj logo ntawm lub ntim sab nraud

Tag

5-amino-1mq yogKev tshawb fawb tshiab hauv kev tshawb fawb hauv metabolic thiab anti -}} kev tshawb fawbCov. Nws yog tshwj xeeb rauKawm Txog NMMT enzyme muaj nuj nqi, tshawb txog cov txheej txheem ntawm cov kab mob metabolic, thiab anti -}} kev txhawb nqa kev tawm tsamCov. Cov koob tshuaj pom zoo yog1-5 mg / kg / hnub.

NEED dab tsi, thov hu raupeb